Antibacterial activity in seaweeds has been reported worldwide, however, the antibacterial activity of southern African seaweeds has not been extensively studied. Results of this study showed that extracting antibacterial compounds by boiling milled seaweed material in 80% ethanol (in water), followed by diffusion of the seaweed extract from a well made in overlay agar was the most effective method for screening seaweeds for antibacterial activity. The antibacterial activity of seaweeds was found to be localised in the meristematic regions of the thallus, or else to occur uniformly throughout the alga. Seasonal variation in the production of antibacterial compounds from seaweeds was reported, and generally the antibacterial activity of southern African seaweeds remained stable during periods of storage. Aromatic and aliphatic compounds were associated with the antibacterial activity of Codium duthieae, whilst that of Zonaria subarticulata was associated with a phenyl-based compound. Interestingly, high levels of metals were found in a number of South African seaweeds, however, these metals were not responsible for the antibacterial activity exhibited by these seaweeds.
|Degree Type||Masters degree|
|Degree Description||MSc (Microbiology)|